Detailed information of TA system TA287777

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1641702..1641882
• Replicon: chromosome
• Accession: NZ_LR134351
• Organism: Staphylococcus aureus strain NCTC13811

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: EL160_RS08365
• Protein ID: WP_001801861.1
• Coordinates: 1641702..1641797 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1641825..1641882 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EL160_RS08330	1636846..1637472	+	627	WP_000669038.1	hypothetical protein	-
EL160_RS08335	1637513..1637857	+	345	WP_000627550.1	DUF3969 family protein	-
EL160_RS08340	1637955..1638527	+	573	WP_000414222.1	hypothetical protein	-
EL160_RS08345	1638676..1640043	-	1368	WP_001093574.1	FRG domain-containing protein	-
EL160_RS08350	1640043..1640612	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
EL160_RS08355	1640805..1641251	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
EL160_RS08365	1641702..1641797	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1641825..1641882	-	58	-	-	Antitoxin
EL160_RS08370	1641920..1642021	+	102	WP_001791232.1	hypothetical protein	-
EL160_RS08375	1642196..1642639	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
EL160_RS08380	1642639..1643082	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
EL160_RS08385	1643082..1643524	-	443	Protein_1583	DUF1433 domain-containing protein	-
EL160_RS08390	1644049..1646468	+	2420	Protein_1584	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T287777 WP_001801861.1 NZ_LR134351:1641702-1641797 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 58 bp

>AT287777 NZ_LR134351:c1641882-1641825 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin