Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 3035766..3036268 Replicon chromosome
Accession NZ_LR134335
Organism Yersinia enterocolitica subsp. palearctica strain NCTC13769

Toxin (Protein)


Gene name yoeB Uniprot ID A0A7T9Y4I7
Locus tag EL202_RS14435 Protein ID WP_005156563.1
Coordinates 3036014..3036268 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7U7FIK7
Locus tag EL202_RS14430 Protein ID WP_005156566.1
Coordinates 3035766..3036017 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL202_RS14420 3031119..3032864 + 1746 WP_005156574.1 ABC transporter ATP-binding protein/permease -
EL202_RS14425 3032849..3035635 + 2787 WP_014609335.1 insulinase family protein -
EL202_RS14430 3035766..3036017 + 252 WP_005156566.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
EL202_RS14435 3036014..3036268 + 255 WP_005156563.1 Txe/YoeB family addiction module toxin Toxin
EL202_RS14440 3036292..3038628 - 2337 WP_005156561.1 mechanosensitive ion channel family protein -
EL202_RS14445 3039047..3041179 + 2133 WP_005156559.1 TonB-dependent siderophore receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10097.60 Da        Isoelectric Point: 9.4486

>T287734 WP_005156563.1 NZ_LR134335:3036014-3036268 [Yersinia enterocolitica subsp. palearctica]
VRIIFSSCSWEDYLYWQQTDKKILKRINELVKNIQRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYEVSGDNLLIAAC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9447.66 Da        Isoelectric Point: 4.4878

>AT287734 WP_005156566.1 NZ_LR134335:3035766-3036017 [Yersinia enterocolitica subsp. palearctica]
MRTISYSEARQNLSTTMVQTVEDRAPILITRQNGTSCVLMSLEEYESLEETAYLLRSPANAKHLMDSIEELRAGKGIQRE
LEE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7T9Y4I7

Antitoxin

Source ID Structure
AlphaFold DB A0A7U7FIK7

References