Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4719934..4720628 Replicon chromosome
Accession NZ_LR134334
Organism Pseudomonas chlororaphis strain NCTC7357

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag EL332_RS21080 Protein ID WP_053268076.1
Coordinates 4719934..4720230 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag EL332_RS21085 Protein ID WP_124323351.1
Coordinates 4720227..4720628 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL332_RS21045 4715471..4716016 - 546 WP_025808153.1 membrane protein -
EL332_RS21050 4716013..4716267 - 255 WP_007926835.1 acyl carrier protein -
EL332_RS21055 4716277..4716537 - 261 WP_025808152.1 acyl carrier protein -
EL332_RS21060 4716512..4717327 - 816 WP_124323349.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
EL332_RS21065 4717303..4718034 - 732 WP_036998144.1 beta-ketoacyl synthase chain length factor -
EL332_RS21070 4718366..4719136 + 771 WP_097305890.1 ParA family protein -
EL332_RS21075 4719262..4719696 - 435 WP_124323350.1 thioredoxin TrxC -
EL332_RS21080 4719934..4720230 + 297 WP_053268076.1 type II toxin-antitoxin system HigB family toxin Toxin
EL332_RS21085 4720227..4720628 + 402 WP_124323351.1 transcriptional regulator Antitoxin
EL332_RS21090 4720633..4722096 - 1464 WP_124323352.1 YdiU family protein -
EL332_RS21095 4722145..4725492 - 3348 WP_124323353.1 mechanosensitive channel MscK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(20-90)

Antitoxin

Cro/C1-type helix-turn-helix domain

(80-132)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11588.41 Da        Isoelectric Point: 10.6515

>T287720 WP_053268076.1 NZ_LR134334:4719934-4720230 [Pseudomonas chlororaphis]
MHIITAKRIWEAKSRWPQSANALETWYRKVKSLNPADFAAIKAVFPATDKVGAFHVFDIGGNKLRIIAVVRYEVRRLYIR
HVLDHHEYDKGRWKEETR

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14925.01 Da        Isoelectric Point: 4.5517

>AT287720 WP_124323351.1 NZ_LR134334:4720227-4720628 [Pseudomonas chlororaphis]
MNVLVRQAAEHWHFVAPVLRKPKTEADYDALVVALDELLDLMGEDENHPVTSLVDIIGDWIEAYDEEHRPMPIASGVDVL
RSLMREHGLTQSDLPGVGAQSVVSEVLSGKRQLNLRQIRWLAERFGVSAEVFI

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References