Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1524644..1525298 Replicon chromosome
Accession NZ_LR134334
Organism Pseudomonas chlororaphis strain NCTC7357

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag EL332_RS06395 Protein ID WP_124324922.1
Coordinates 1524644..1524994 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag EL332_RS06400 Protein ID WP_124324923.1
Coordinates 1524984..1525298 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL332_RS06385 1521395..1522927 + 1533 WP_053279911.1 NADH-quinone oxidoreductase subunit M -
EL332_RS06390 1522935..1524398 + 1464 WP_009049791.1 NADH-quinone oxidoreductase subunit NuoN -
EL332_RS06395 1524644..1524994 + 351 WP_124324922.1 toxin Toxin
EL332_RS06400 1524984..1525298 + 315 WP_124324923.1 transcriptional regulator Antitoxin
EL332_RS06405 1525476..1527218 - 1743 WP_025804713.1 ABC transporter substrate-binding protein -
EL332_RS06410 1527269..1527541 - 273 WP_025804714.1 DUF2160 domain-containing protein -
EL332_RS06415 1527552..1528352 - 801 WP_007929618.1 carbohydrate ABC transporter permease -
EL332_RS06420 1528364..1529230 - 867 WP_124324924.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13791.76 Da        Isoelectric Point: 9.4187

>T287717 WP_124324922.1 NZ_LR134334:1524644-1524994 [Pseudomonas chlororaphis]
MDALFIELPPFQRHRQDYLDDELFRSLQLELLKAPEAGDLIEGVGGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQFWL
FTLYAKNEQNDLTSHQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11921.84 Da        Isoelectric Point: 10.7886

>AT287717 WP_124324923.1 NZ_LR134334:1524984-1525298 [Pseudomonas chlororaphis]
MKRDIFSELVEGFDTLAKERQGKLTLRTHKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References