287662

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3735312..3735966 Replicon chromosome
Accession NZ_LR134318
Organism Pseudomonas fluorescens strain NCTC9428

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag EL257_RS16850 Protein ID WP_126364509.1
Coordinates 3735312..3735662 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag EL257_RS16855 Protein ID WP_126364511.1
Coordinates 3735652..3735966 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL257_RS16840 3731994..3733526 + 1533 WP_016775285.1 NADH-quinone oxidoreductase subunit M -
EL257_RS16845 3733534..3734997 + 1464 WP_024013420.1 NADH-quinone oxidoreductase subunit NuoN -
EL257_RS16850 3735312..3735662 + 351 WP_126364509.1 toxin Toxin
EL257_RS16855 3735652..3735966 + 315 WP_126364511.1 transcriptional regulator Antitoxin
EL257_RS16860 3736082..3737824 - 1743 WP_126364513.1 ABC transporter substrate-binding protein -
EL257_RS16865 3737872..3738144 - 273 WP_126364515.1 DUF2160 domain-containing protein -
EL257_RS16870 3738155..3738955 - 801 WP_041477086.1 carbohydrate ABC transporter permease -
EL257_RS16875 3738965..3739831 - 867 WP_007912484.1 sugar ABC transporter permease -
EL257_RS16880 3739828..3740937 - 1110 WP_126364517.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13930.74 Da        Isoelectric Point: 6.4721

>T287662 WP_126364509.1 NZ_LR134318:3735312-3735662 [Pseudomonas fluorescens]
MDALFIELPAFQKHRDDYLDEDLFLSFQLELLKNPEAGDLIEETGGLRKIRFCDQRRGKGKRSGLRVIYYWWSGFDQFWL
FTVYSKSDQNDLTPAQKKLFRQTLDRELNTRTHYET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11876.72 Da        Isoelectric Point: 9.9896

>AT287662 WP_126364511.1 NZ_LR134318:3735652-3735966 [Pseudomonas fluorescens]
MKRDIFSELMDGLDALADERQGKITLRTHKVQLPKLVPITAEEVVAIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQATTLIRLVERFPQTIEQLAALS

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References