Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1217072..1217766 Replicon chromosome
Accession NZ_LR134306
Organism Yersinia pseudotuberculosis strain NCTC3571

Toxin (Protein)


Gene name mqsR Uniprot ID A0A0E1NW62
Locus tag EL172_RS05415 Protein ID WP_002214787.1
Coordinates 1217072..1217368 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID Q666X1
Locus tag EL172_RS05420 Protein ID WP_002209924.1
Coordinates 1217368..1217766 (+) Length 133 a.a.

Genomic Context

EL172_RS05385EL172_RS05395EL172_RS05405EL172_RS05410EL172_RS05415EL172_RS05420EL172_RS05430EL172_RS23155EL172_RS05400EL172_RS05425EL172_RS05435EL172_RS05440EL172_RS05445EL172_RS05450
Location: 1212196..1213713 (1518 bp)
Type: Others
Protein ID: WP_002209930.1
Location: 1214146..1215360 (1215 bp)
Type: Others
Protein ID: Protein_1000
Location: 1216223..1216483 (261 bp)
Type: Others
Protein ID: WP_002214785.1
Location: 1216546..1216908 (363 bp)
Type: Others
Protein ID: WP_002209925.1
Location: 1217072..1217368 (297 bp)
Type: Toxin
Protein ID: WP_002214787.1
Location: 1217368..1217766 (399 bp)
Type: Antitoxin
Protein ID: WP_002209924.1
Location: 1220757..1221083 (327 bp)
Type: Others
Protein ID: WP_002209922.1
Location: 1221076..1221228 (153 bp)
Type: Others
Protein ID: WP_002209921.1
Location: 1215416..1215625 (210 bp)
Type: Others
Protein ID: WP_050320983.1
Location: 1218166..1220457 (2292 bp)
Type: Others
Protein ID: WP_050320982.1
Location: 1221242..1221442 (201 bp)
Type: Others
Protein ID: WP_002209920.1
Location: 1221624..1221956 (333 bp)
Type: Others
Protein ID: WP_002214791.1
Location: 1221962..1222198 (237 bp)
Type: Others
Protein ID: WP_002214792.1
Location: 1222211..1222576 (366 bp)
Type: Others
Protein ID: WP_002209919.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EL172_RS053851212196..1213713+1518WP_002209930.1lysine--tRNA ligase-
EL172_RS053951214146..1215360+1215Protein_1000tyrosine-type recombinase/integrase-
EL172_RS054001215416..1215625-210WP_050320983.1hypothetical protein-
EL172_RS054051216223..1216483+261WP_002214785.1type II toxin-antitoxin system RelE/ParE family toxin-
EL172_RS054101216546..1216908+363WP_002209925.1helix-turn-helix domain-containing protein-
EL172_RS054151217072..1217368+297WP_002214787.1type II toxin-antitoxin system MqsR family toxinToxin
EL172_RS054201217368..1217766+399WP_002209924.1type II toxin-antitoxin system MqsA family antitoxinAntitoxin
EL172_RS054251218166..1220457-2292WP_050320982.1toprim domain-containing protein-
EL172_RS054301220757..1221083+327WP_002209922.1type II toxin-antitoxin system RelE/ParE family toxin-
EL172_RS231551221076..1221228+153WP_002209921.1hypothetical protein-
EL172_RS054351221242..1221442-201WP_002209920.1AlpA family transcriptional regulator-
EL172_RS054401221624..1221956-333WP_002214791.1hypothetical protein-
EL172_RS054451221962..1222198-237WP_002214792.1hypothetical protein-
EL172_RS054501222211..1222576-366WP_002209919.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(75-128)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11319.12 Da        Isoelectric Point: 7.8810

>T287564 WP_002214787.1 NZ_LR134306:1217072-1217368 [Yersinia pseudotuberculosis]
MEKRTPHTRLLKVKELVLKGNIKTTRTARDGAEELGLSFRDMCDAVSELISADFYKSMTTHQDHTIWQDVYRPMLSCGRV
YLKITVIDDVLNVSFKEI

Download         Length: 297 bp

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14657.17 Da        Isoelectric Point: 8.4923

>AT287564 WP_002209924.1 NZ_LR134306:1217368-1217766 [Yersinia pseudotuberculosis]
MMKCPVCGGVELIHEARDVPFTYKGRKFIVEGVIGQHCPACGETVMTEAESDVYAAKTMLLRKMVNTESIAPAYIVQIRK
KLGLNQREASEIFGGGVNAFSRYEKGKALPHPSTIKLLQVLDKHPELLNEIR

Download         Length: 399 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A0E1NW62

Antitoxin

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Source
ID
Structure
AlphaFold DBQ666X1

References