Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2190455..2190639 Replicon chromosome
Accession NZ_LR134305
Organism Staphylococcus aureus strain NCTC1803

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag EL119_RS11570 Protein ID WP_000482647.1
Coordinates 2190532..2190639 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2190455..2190515 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL119_RS11545 2185909..2186076 - 168 WP_041204334.1 hypothetical protein -
EL119_RS11555 2186307..2188040 - 1734 WP_000486497.1 ABC transporter ATP-binding protein/permease -
EL119_RS11560 2188065..2189828 - 1764 WP_001064817.1 ABC transporter ATP-binding protein/permease -
- 2190455..2190515 + 61 - - Antitoxin
EL119_RS11570 2190532..2190639 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
EL119_RS11575 2190773..2191159 - 387 WP_000779350.1 flippase GtxA -
EL119_RS11580 2191427..2192569 + 1143 WP_001176868.1 glycerate kinase -
EL119_RS11585 2192629..2193288 + 660 WP_000831299.1 hypothetical protein -
EL119_RS11590 2193474..2194685 + 1212 WP_001191928.1 multidrug effflux MFS transporter -
EL119_RS11595 2194808..2195281 - 474 WP_000456493.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T287561 WP_000482647.1 NZ_LR134305:c2190639-2190532 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT287561 NZ_LR134305:2190455-2190515 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References