Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-SprA2AS/-
Location 1898566..1898764 Replicon chromosome
Accession NZ_LR134305
Organism Staphylococcus aureus strain NCTC1803

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag EL119_RS10030 Protein ID WP_001802298.1
Coordinates 1898660..1898764 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1898566..1898604 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL119_RS10010 1894675..1895340 - 666 WP_001024100.1 SDR family oxidoreductase -
EL119_RS10015 1895492..1895812 + 321 WP_094754121.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EL119_RS10020 1895814..1896794 + 981 WP_000019740.1 CDF family zinc efflux transporter CzrB -
EL119_RS10025 1897060..1898151 + 1092 WP_000495692.1 hypothetical protein -
- 1898566..1898604 + 39 - - Antitoxin
EL119_RS10030 1898660..1898764 - 105 WP_001802298.1 hypothetical protein Toxin
EL119_RS14605 1898925..1899408 - 484 Protein_1852 recombinase family protein -
EL119_RS10040 1899451..1900571 - 1121 Protein_1853 SAP domain-containing protein -
EL119_RS10045 1901620..1902477 - 858 WP_000370943.1 Cof-type HAD-IIB family hydrolase -
EL119_RS10050 1902545..1903327 - 783 WP_000909235.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T287559 WP_001802298.1 NZ_LR134305:c1898764-1898660 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT287559 NZ_LR134305:1898566-1898604 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References