Detailed information of TA system TA287554

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1541756..1541936
• Replicon: chromosome
• Accession: NZ_LR134305
• Organism: Staphylococcus aureus strain NCTC1803

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: EL119_RS07850
• Protein ID: WP_001801861.1
• Coordinates: 1541756..1541851 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1541879..1541936 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EL119_RS07815	1537160..1537786	+	627	WP_126498393.1	hypothetical protein	-
EL119_RS07820	1537827..1538168	+	342	WP_000627544.1	DUF3969 family protein	-
EL119_RS07825	1538269..1538841	+	573	WP_000414210.1	hypothetical protein	-
EL119_RS07830	1539217..1540053	+	837	WP_000190484.1	ABC transporter ATP-binding protein	-
EL119_RS07840	1540859..1541305	-	447	WP_000747806.1	DUF1433 domain-containing protein	-
EL119_RS07850	1541756..1541851	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1541879..1541936	-	58	-	-	Antitoxin
EL119_RS07855	1541974..1542075	+	102	WP_001791232.1	hypothetical protein	-
EL119_RS07860	1542061..1542240	-	180	Protein_1479	transposase	-
EL119_RS07865	1542428..1542802	-	375	WP_000695817.1	DUF1433 domain-containing protein	-
EL119_RS07870	1542792..1543172	-	381	WP_001035978.1	DUF1433 domain-containing protein	-
EL119_RS07875	1543380..1543820	-	441	WP_000759945.1	DUF1433 domain-containing protein	-
EL119_RS07880	1543865..1545478	+	1614	WP_000926709.1	hypothetical protein	-
EL119_RS07885	1545493..1545792	+	300	WP_000095391.1	WXG100 family type VII secretion target	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T287554 WP_001801861.1 NZ_LR134305:1541756-1541851 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 58 bp

>AT287554 NZ_LR134305:c1541936-1541879 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin