287548

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2463835..2464019 Replicon chromosome
Accession NZ_LR134304
Organism Staphylococcus schweitzeri strain NCTC13712

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2K4AFL5
Locus tag EL116_RS12230 Protein ID WP_000482651.1
Coordinates 2463912..2464019 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2463835..2463895 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL116_RS12220 2459580..2461313 - 1734 WP_047549901.1 ABC transporter ATP-binding protein/permease -
EL116_RS12225 2461338..2463101 - 1764 WP_047529842.1 ABC transporter ATP-binding protein/permease -
- 2463835..2463895 + 61 - - Antitoxin
EL116_RS12230 2463912..2464019 - 108 WP_000482651.1 type I toxin-antitoxin system Fst family toxin Toxin
EL116_RS12235 2464152..2464538 - 387 WP_047426382.1 flippase GtxA -
EL116_RS12240 2464806..2465948 + 1143 WP_047449388.1 glycerate kinase -
EL116_RS12245 2466007..2466660 + 654 WP_047549905.1 membrane protein -
EL116_RS12250 2466853..2468064 + 1212 WP_047549907.1 multidrug effflux MFS transporter -
EL116_RS12255 2468179..2468658 - 480 WP_047549911.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3984.75 Da        Isoelectric Point: 11.0582

>T287548 WP_000482651.1 NZ_LR134304:c2464019-2463912 [Staphylococcus schweitzeri]
MFNLLINIMTSAISGCLVAFFAHWLRTRSNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT287548 NZ_LR134304:2463835-2463895 [Staphylococcus schweitzeri]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTATTGCCGTAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K4AFL5

Antitoxin

Download structure file

References