Detailed information of TA system TA287543

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1012579..1012828
• Replicon: chromosome
• Accession: NZ_LR134304
• Organism: Staphylococcus schweitzeri strain NCTC13712

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: EL116_RS05055
• Protein ID: WP_000623369.1
• Coordinates: 1012579..1012686 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1012681..1012828 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EL116_RS05030	1009254..1009823	-	570	WP_047424746.1	competence protein ComK	-
EL116_RS05035	1010033..1010251	+	219	WP_047531347.1	IDEAL domain-containing protein	-
EL116_RS05040	1010332..1011318	-	987	WP_047531349.1	lipoate--protein ligase	-
EL116_RS05045	1011515..1011691	+	177	WP_000214898.1	YkvS family protein	-
EL116_RS05050	1011706..1012308	+	603	WP_047531351.1	CPBP family intramembrane metalloprotease	-
EL116_RS05055	1012579..1012686	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	1012681..1012828	-	148	-	-	Antitoxin
EL116_RS05060	1013283..1013567	+	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
EL116_RS05065	1013611..1015575	+	1965	WP_047550786.1	bacteriocin-associated integral membrane family protein	-
EL116_RS05070	1015578..1015898	+	321	WP_000668623.1	YxeA family protein	-
EL116_RS05075	1015895..1016536	+	642	WP_047550789.1	ABC transporter ATP-binding protein	-
EL116_RS05080	1016625..1016915	-	291	WP_078101769.1	hypothetical protein	-
EL116_RS05085	1017209..1017496	+	288	WP_047531360.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T287543 WP_000623369.1 NZ_LR134304:1012579-1012686 [Staphylococcus schweitzeri]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 148 bp

>AT287543 NZ_LR134304:c1012828-1012681 [Staphylococcus schweitzeri]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGGAACATGTCGCCTATTGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTTCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin