287537

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-SprA2AS/-
Location 793318..793625 Replicon chromosome
Accession NZ_LR134304
Organism Staphylococcus schweitzeri strain NCTC13712

Toxin (Protein)


Gene name txpA Uniprot ID Q2FWU9
Locus tag EL116_RS03845 Protein ID WP_011447039.1
Coordinates 793318..793494 (+) Length 59 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 793484..793625 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL116_RS03825 788719..789654 + 936 WP_047427095.1 thioredoxin-disulfide reductase -
EL116_RS03830 790002..790913 + 912 WP_031787679.1 RNase adapter RapZ -
EL116_RS03835 790910..791911 + 1002 WP_047551142.1 YvcK family protein -
EL116_RS03840 792017..792961 + 945 WP_047427100.1 DNA-binding protein WhiA -
EL116_RS03845 793318..793494 + 177 WP_011447039.1 putative holin-like toxin Toxin
- 793484..793625 - 142 - - Antitoxin
EL116_RS03855 793705..794007 + 303 WP_047530997.1 phage holin -
EL116_RS03860 794056..794217 + 162 Protein_717 N-acetylmuramoyl-L-alanine amidase -
EL116_RS03870 794587..795174 + 588 WP_001049165.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP -
EL116_RS03875 795353..796987 + 1635 WP_047551149.1 NAD-dependent malic enzyme -
EL116_RS03880 797186..798088 - 903 WP_047551151.1 TIGR01777 family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(30-58)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6849.45 Da        Isoelectric Point: 10.6777

>T287537 WP_011447039.1 NZ_LR134304:793318-793494 [Staphylococcus schweitzeri]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Download         Length: 177 bp

Antitoxin


Download         Length: 142 bp

>AT287537 NZ_LR134304:c793625-793484 [Staphylococcus schweitzeri]
ATATATAGAAAAAGGGCAACATGCGCAAACACGTTACCCTAATGAACCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 7NS1

Antitoxin

Download structure file

References