Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1908882..1909582 Replicon chromosome
Accession NZ_LR134299
Organism Pseudomonas putida strain NCTC13186

Toxin (Protein)


Gene name mqsR Uniprot ID Q88F93
Locus tag EL224_RS08910 Protein ID WP_010954960.1
Coordinates 1908882..1909178 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID I7AUJ7
Locus tag EL224_RS08915 Protein ID WP_003254235.1
Coordinates 1909181..1909582 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL224_RS08890 1904874..1906052 - 1179 WP_010954964.1 efflux RND transporter periplasmic adaptor subunit -
EL224_RS08895 1906265..1906741 + 477 WP_010954963.1 sigma-70 family RNA polymerase sigma factor -
EL224_RS08900 1906910..1907389 + 480 WP_010954962.1 hypothetical protein -
EL224_RS08905 1907462..1908787 + 1326 WP_010954961.1 MFS transporter -
EL224_RS08910 1908882..1909178 + 297 WP_010954960.1 type II toxin-antitoxin system MqsR family toxin Toxin
EL224_RS08915 1909181..1909582 + 402 WP_003254235.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
EL224_RS08920 1909654..1911336 - 1683 WP_010954959.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
EL224_RS08925 1911872..1912621 + 750 WP_003254232.1 electron transfer flavoprotein subunit beta/FixA family protein -
EL224_RS08930 1912622..1913551 + 930 WP_010954958.1 FAD-binding protein -
EL224_RS08935 1913627..1914448 + 822 WP_010954957.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11133.22 Da        Isoelectric Point: 10.2271

>T287505 WP_010954960.1 NZ_LR134299:1908882-1909178 [Pseudomonas putida]
MEKRMPHCPLERVKALAAARRIRPTGAALKGAKALGMDFPGMLEVITSLKRTDFYKSMTSHIDHRVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14684.76 Da        Isoelectric Point: 4.9531

>AT287505 WP_003254235.1 NZ_LR134299:1909181-1909582 [Pseudomonas putida]
MRCPICGGSELAPDIQGMPYSYKGEMTVIPEVSGDYCSACGECVLSHDEAMRVSHLMTAFERQVNANVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q88F93

Antitoxin

Source ID Structure
AlphaFold DB I7AUJ7

References