287456

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 352795..353492 Replicon chromosome
Accession NZ_LR134287
Organism Neisseria animalis strain NCTC10212

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag EL111_RS01715 Protein ID WP_123795298.1
Coordinates 352795..353091 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag EL111_RS01720 Protein ID WP_123795299.1
Coordinates 353094..353492 (+) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL111_RS01670 348278..349267 + 990 WP_123795291.1 NAD(P)-dependent glycerol-3-phosphate dehydrogenase -
EL111_RS01675 349369..349692 + 324 WP_123795292.1 hypothetical protein -
EL111_RS01680 349706..350005 + 300 WP_123795293.1 cell division protein ZapA -
EL111_RS01690 350326..351102 + 777 WP_123795294.1 triose-phosphate isomerase -
EL111_RS01695 351108..351455 + 348 WP_123795295.1 preprotein translocase subunit SecG -
EL111_RS01705 351914..352171 + 258 WP_123795296.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
EL111_RS01710 352171..352590 + 420 WP_123795297.1 type II toxin-antitoxin system VapC family toxin -
EL111_RS01715 352795..353091 + 297 WP_123795298.1 type II toxin-antitoxin system MqsR family toxin Toxin
EL111_RS01720 353094..353492 + 399 WP_123795299.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
EL111_RS01725 353638..353949 + 312 WP_123795300.1 DNA-binding transcriptional regulator -
EL111_RS01730 355041..356669 + 1629 WP_123795301.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-127)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11091.95 Da        Isoelectric Point: 9.7581

>T287456 WP_123795298.1 NZ_LR134287:352795-353091 [Neisseria animalis]
MEKRIPHTKLAKVKALLKSGKVRTTQTALIGAVQMGFDYDSMLAVVHNLTPADFYKSMTTHANHTIWQDVYRPDTDLGRV
YLKLTVIDDALIVSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14662.85 Da        Isoelectric Point: 7.6302

>AT287456 WP_123795299.1 NZ_LR134287:353094-353492 [Neisseria animalis]
MKCPVCNQAELIRDTRDMPYTYKGQDTVIPAVTADYCPACNEVVTDEAESRRIMAAMQAFNKQINSATADPAYIQSVRKK
LQLDQRQAAEIFGGGVNAFSRYETGKATPPLALLQLFKILDKHPALLSEIRP

Download         Length: 399 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References