287437

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2551618..2551802 Replicon chromosome
Accession NZ_LR134271
Organism Staphylococcus aureus strain NCTC7988

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag EL099_RS13315 Protein ID WP_000482647.1
Coordinates 2551695..2551802 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2551618..2551678 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL099_RS13290 2547072..2547239 - 168 WP_041204334.1 hypothetical protein -
EL099_RS13300 2547470..2549203 - 1734 WP_000486497.1 ABC transporter ATP-binding protein/permease -
EL099_RS13305 2549228..2550991 - 1764 WP_001064817.1 ABC transporter ATP-binding protein/permease -
- 2551618..2551678 + 61 - - Antitoxin
EL099_RS13315 2551695..2551802 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
EL099_RS13320 2551936..2552322 - 387 WP_000779350.1 flippase GtxA -
EL099_RS13325 2552590..2553732 + 1143 WP_001176868.1 glycerate kinase -
EL099_RS13330 2553792..2554451 + 660 WP_000831299.1 hypothetical protein -
EL099_RS13335 2554637..2555848 + 1212 WP_001191928.1 multidrug effflux MFS transporter -
EL099_RS13340 2555971..2556444 - 474 WP_000456493.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T287437 WP_000482647.1 NZ_LR134271:c2551802-2551695 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT287437 NZ_LR134271:2551618-2551678 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References