Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2261314..2261577 Replicon chromosome
Accession NZ_LR134271
Organism Staphylococcus aureus strain NCTC7988

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag EL099_RS11780 Protein ID WP_001802298.1
Coordinates 2261473..2261577 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2261314..2261478 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL099_RS11760 2257488..2258153 - 666 WP_001024100.1 SDR family oxidoreductase -
EL099_RS11765 2258305..2258625 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EL099_RS11770 2258627..2259607 + 981 WP_000019740.1 CDF family zinc efflux transporter CzrB -
EL099_RS11775 2259873..2260964 + 1092 WP_000495692.1 hypothetical protein -
- 2261314..2261478 + 165 - - Antitoxin
EL099_RS11780 2261473..2261577 - 105 WP_001802298.1 hypothetical protein Toxin
EL099_RS14855 2261738..2262221 - 484 Protein_2183 recombinase family protein -
EL099_RS11790 2262264..2263384 - 1121 Protein_2184 SAP domain-containing protein -
EL099_RS11795 2264433..2265290 - 858 WP_000370943.1 Cof-type HAD-IIB family hydrolase -
EL099_RS11800 2265358..2266140 - 783 WP_070040383.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T287434 WP_001802298.1 NZ_LR134271:c2261577-2261473 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT287434 NZ_LR134271:2261314-2261478 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References