Detailed information of TA system TA287430

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1897768..1897948
• Replicon: chromosome
• Accession: NZ_LR134271
• Organism: Staphylococcus aureus strain NCTC7988

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: EL099_RS09565
• Protein ID: WP_001801861.1
• Coordinates: 1897768..1897863 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1897891..1897948 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EL099_RS09530	1893172..1893798	+	627	WP_000669034.1	hypothetical protein	-
EL099_RS09535	1893839..1894180	+	342	WP_000627544.1	DUF3969 family protein	-
EL099_RS09540	1894281..1894853	+	573	WP_000414210.1	hypothetical protein	-
EL099_RS09545	1895229..1896065	+	837	WP_000190484.1	ABC transporter ATP-binding protein	-
EL099_RS09555	1896871..1897317	-	447	WP_000747806.1	DUF1433 domain-containing protein	-
EL099_RS09565	1897768..1897863	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1897891..1897948	-	58	-	-	Antitoxin
EL099_RS09570	1897986..1898087	+	102	WP_001791232.1	hypothetical protein	-
EL099_RS09575	1898073..1898252	-	180	Protein_1803	transposase	-
EL099_RS09580	1898440..1898814	-	375	WP_000695817.1	DUF1433 domain-containing protein	-
EL099_RS09585	1898804..1899184	-	381	WP_070040298.1	DUF1433 domain-containing protein	-
EL099_RS09590	1899392..1899832	-	441	WP_000759945.1	DUF1433 domain-containing protein	-
EL099_RS09595	1899877..1901490	+	1614	WP_000926709.1	hypothetical protein	-
EL099_RS09600	1901505..1901804	+	300	WP_000095391.1	WXG100 family type VII secretion target	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / lukS-PV / lukS-PV	1896053..1950958	54905

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T287430 WP_001801861.1 NZ_LR134271:1897768-1897863 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 58 bp

>AT287430 NZ_LR134271:c1897948-1897891 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin