287403

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 192353..192876 Replicon chromosome
Accession NZ_LR134267
Organism Staphylococcus pseudintermedius strain NCTC5661

Toxin (Protein)


Gene name yoeB Uniprot ID A0A317Z6J3
Locus tag EL085_RS00855 Protein ID WP_037542127.1
Coordinates 192610..192876 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A2P5PI69
Locus tag EL085_RS00850 Protein ID WP_015729747.1
Coordinates 192353..192610 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL085_RS00835 188401..189207 + 807 WP_126510848.1 arylamine N-acetyltransferase -
EL085_RS00840 189501..189995 - 495 WP_015729749.1 membrane protein -
EL085_RS00845 190255..192159 + 1905 WP_126510849.1 triacylglycerol lipase -
EL085_RS00850 192353..192610 + 258 WP_015729747.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EL085_RS00855 192610..192876 + 267 WP_037542127.1 Txe/YoeB family addiction module toxin Toxin
EL085_RS00860 193237..193338 - 102 WP_019169745.1 DUF2648 domain-containing protein -
EL085_RS00865 193352..194845 - 1494 WP_014612817.1 malate dehydrogenase (quinone) -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10555.10 Da        Isoelectric Point: 10.1602

>T287403 WP_037542127.1 NZ_LR134267:192610-192876 [Staphylococcus pseudintermedius]
MGNYSVLIKNSAKNDLKKIKKSLLKEQFSKIIEVLKINPYEASQSFEKLQPKHSARYSRRLNHQHRVVYTVDDEKREVYI
FSAWSYYE

Download         Length: 267 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9836.85 Da        Isoelectric Point: 4.1100

>AT287403 WP_015729747.1 NZ_LR134267:192353-192610 [Staphylococcus pseudintermedius]
MIIKTPTNARKEFYELLKQVNDNHEPIIISGSKSENNAVIVSQEDWDGIQETLFLEYTGTMDKVRAREKDDSGYTNIDDI
DWDNL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A317Z6J3

Antitoxin

Source ID Structure
AlphaFold DB A0A2P5PI69

References