Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1537514..1538026 Replicon chromosome
Accession NZ_LR134266
Organism Streptococcus viridans strain NCTC3166

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag EL081_RS07995 Protein ID WP_126404733.1
Coordinates 1537514..1537768 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag EL081_RS08000 Protein ID WP_003014291.1
Coordinates 1537772..1538026 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL081_RS07975 1533434..1534306 - 873 WP_126404729.1 MetQ/NlpA family ABC transporter substrate-binding protein -
EL081_RS07980 1534339..1535166 - 828 WP_126404730.1 amino acid ABC transporter substrate-binding protein -
EL081_RS07985 1535293..1536435 - 1143 WP_126404731.1 amidohydrolase -
EL081_RS07990 1536624..1537340 - 717 WP_126404732.1 YebC/PmpR family DNA-binding transcriptional regulator -
EL081_RS07995 1537514..1537768 - 255 WP_126404733.1 Txe/YoeB family addiction module toxin Toxin
EL081_RS08000 1537772..1538026 - 255 WP_003014291.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EL081_RS08005 1538260..1539354 - 1095 WP_126404734.1 nucleotidyltransferase -
EL081_RS08010 1539361..1540170 - 810 WP_126404735.1 class I SAM-dependent methyltransferase -
EL081_RS08020 1540424..1540777 - 354 WP_126404737.1 ribosome silencing factor -
EL081_RS08025 1540792..1541292 - 501 WP_126404738.1 cysteine hydrolase -
EL081_RS08030 1541293..1541889 - 597 WP_126404739.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
EL081_RS08035 1541889..1542518 - 630 WP_126404740.1 nicotinate-nucleotide adenylyltransferase -
EL081_RS08040 1542540..1542851 - 312 WP_006595720.1 ribosome assembly RNA-binding protein YhbY -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10054.53 Da        Isoelectric Point: 7.9774

>T287402 WP_126404733.1 NZ_LR134266:c1537768-1537514 [Streptococcus viridans]
MLLKFTEDAWKDYCYWQSQDKKTLKRINTLIKEIQKDPFAGIGKPEPLKYDFQGAWSRRIDAENRLIYMIDESGVAFLSF
KDHY

Download         Length: 255 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9703.98 Da        Isoelectric Point: 4.6768

>AT287402 WP_003014291.1 NZ_LR134266:c1538026-1537772 [Streptococcus viridans]
MEAVVYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVISKSEWDSLQETLRLAQNKELSDKVLRGMAEVRAGQVQLH
EIEG

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References