Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-sprA1AS/-
Location 1013315..1013476 Replicon chromosome
Accession NZ_LR134242
Organism Staphylococcus warneri strain NCTC4133

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag EL068_RS05020 Protein ID WP_015364873.1
Coordinates 1013315..1013410 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1013442..1013476 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL068_RS05010 1009286..1012219 + 2934 WP_126510295.1 AAA family ATPase -
EL068_RS05015 1012219..1013160 + 942 WP_002466800.1 3'-5' exoribonuclease YhaM -
EL068_RS05020 1013315..1013410 + 96 WP_015364873.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1013442..1013476 - 35 - - Antitoxin
EL068_RS05025 1013562..1014554 - 993 WP_002466825.1 peptidylprolyl isomerase -
EL068_RS05030 1014732..1015289 - 558 WP_002466819.1 DUF3267 domain-containing protein -
EL068_RS05035 1015484..1015855 - 372 WP_002452114.1 YtxH domain-containing protein -
EL068_RS05040 1015933..1016358 - 426 WP_058710124.1 HIT family protein -
EL068_RS05045 1016490..1017230 + 741 WP_002466806.1 ABC transporter ATP-binding protein -
EL068_RS05050 1017223..1018446 + 1224 WP_126510296.1 ABC transporter permease -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3610.26 Da        Isoelectric Point: 8.0878

>T287347 WP_015364873.1 NZ_LR134242:1013315-1013410 [Staphylococcus warneri]
MTEIFVHIATTVISGCIVTLFAHWLRHRNDK

Download         Length: 96 bp


Antitoxin


Download         Length: 35 bp

>AT287347 NZ_LR134242:c1013476-1013442 [Staphylococcus warneri]
ACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References