287343

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 51708..52218 Replicon chromosome
Accession NZ_LR134242
Organism Staphylococcus warneri strain NCTC4133

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag EL068_RS00225 Protein ID WP_049416776.1
Coordinates 51955..52218 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag EL068_RS00220 Protein ID WP_049416774.1
Coordinates 51708..51962 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL068_RS00205 47216..48538 + 1323 WP_049416769.1 PrsW family intramembrane metalloprotease -
EL068_RS00210 48689..49126 + 438 WP_002466379.1 hypothetical protein -
EL068_RS00215 49253..51463 - 2211 WP_126510159.1 YSIRK-type signal peptide-containing protein -
EL068_RS00220 51708..51962 + 255 WP_049416774.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EL068_RS00225 51955..52218 + 264 WP_049416776.1 Txe/YoeB family addiction module toxin Toxin
EL068_RS00230 52376..53824 - 1449 WP_049416778.1 aldehyde dehydrogenase family protein -
EL068_RS00235 53986..55095 + 1110 WP_050969455.1 NAD(P)-dependent alcohol dehydrogenase -
EL068_RS00240 55400..56770 + 1371 WP_049416781.1 citrate:proton symporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10414.10 Da        Isoelectric Point: 9.8163

>T287343 WP_049416776.1 NZ_LR134242:51955-52218 [Staphylococcus warneri]
MSRLNILFTPDAFEDYKYWQIHDKKLLKKINHLIKCINRNGPLEGEGKPEALKGNFKGYYSRRINFEHRLVYKVHDSEII
IVSCKYQ

Download         Length: 264 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9373.33 Da        Isoelectric Point: 4.0334

>AT287343 WP_049416774.1 NZ_LR134242:51708-51962 [Staphylococcus warneri]
MAIVSYSIARKNFRSLIDKVNNDSDAVTITTNDSNAVLISESDYNAMMETLYLQQSPANAQHLAKSIEDVERGNTIEVDL
ESYE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References