Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 205269..205491 Replicon chromosome
Accession NZ_LR134228
Organism Escherichia coli strain NCTC9699

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag EL118_RS00990 Protein ID WP_000141634.1
Coordinates 205384..205491 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 205269..205335 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL118_RS00970 200710..201612 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
EL118_RS00975 201623..202606 + 984 WP_001196496.1 dipeptide ABC transporter ATP-binding protein -
EL118_RS00980 202603..203607 + 1005 WP_032256837.1 dipeptide ABC transporter ATP-binding subunit DppF -
EL118_RS00985 203637..204908 - 1272 WP_001295225.1 transporter -
- 205269..205335 - 67 - - Antitoxin
EL118_RS00990 205384..205491 + 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
EL118_RS00995 205578..207257 - 1680 WP_089622392.1 cellulose biosynthesis protein BcsG -
EL118_RS01000 207254..207445 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
EL118_RS01005 207442..209013 - 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
EL118_RS01010 209286..209474 + 189 WP_001063318.1 YhjR family protein -
EL118_RS01015 209486..210238 + 753 WP_000279528.1 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T287185 WP_000141634.1 NZ_LR134228:205384-205491 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

Antitoxin


Download         Length: 67 bp

>AT287185 NZ_LR134228:c205335-205269 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References