Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | DinJ-YafQ (relBE)/YafQ-RelB |
Location | 3634837..3635378 | Replicon | chromosome |
Accession | NZ_LR134216 | ||
Organism | Escherichia coli strain NCTC10973 |
Toxin (Protein)
Gene name | yafQ | Uniprot ID | Q47149 |
Locus tag | EL103_RS17660 | Protein ID | WP_000615983.1 |
Coordinates | 3635100..3635378 (+) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | dinJ | Uniprot ID | Q47150 |
Locus tag | EL103_RS17655 | Protein ID | WP_000729703.1 |
Coordinates | 3634837..3635097 (+) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EL103_RS17640 | 3630888..3632981 | + | 2094 | WP_001140826.1 | flagellar biosynthesis protein FlhA | - |
EL103_RS17645 | 3633205..3633702 | - | 498 | WP_000006255.1 | REP-associated tyrosine transposase RayT | - |
EL103_RS17650 | 3633878..3634627 | - | 750 | WP_113402119.1 | C40 family peptidase | - |
EL103_RS17655 | 3634837..3635097 | + | 261 | WP_000729703.1 | type II toxin-antitoxin system antitoxin DinJ | Antitoxin |
EL103_RS17660 | 3635100..3635378 | + | 279 | WP_000615983.1 | type II toxin-antitoxin system mRNA interferase toxin YafQ | Toxin |
EL103_RS17665 | 3635534..3636274 | + | 741 | WP_001225679.1 | murein L,D-transpeptidase | - |
EL103_RS17670 | 3636245..3637012 | - | 768 | WP_000333380.1 | class II glutamine amidotransferase | - |
EL103_RS17675 | 3637218..3637796 | - | 579 | WP_000284050.1 | D-sedoheptulose 7-phosphate isomerase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | gmhA/lpcA / clpV/tssH / tssA / tssA / hcp1/tssD1 | 3633878..3660623 | 26745 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
PDB | 4Q2U |
Antitoxin
Source | ID | Structure |
---|---|---|
PDB | 4Q2U | |
AlphaFold DB | A0A5F1F716 |