Detailed information of TA system TA287071

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 675168..675429
• Replicon: chromosome
• Accession: NZ_LR134215
• Organism: Shimwellia blattae strain NCTC12127

Toxin (Protein)

• Gene name: hok
• Uniprot ID: -
• Locus tag: EL083_RS03210
• Protein ID: WP_014715816.1
• Coordinates: 675268..675429 (+)
• Length: 54 a.a.

Antitoxin (RNA)

Gene name	sok
Locus tag	-
Coordinates	675168..675204 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EL083_RS03185	670864..671154	+	291	WP_002444900.1	citrate lyase acyl carrier protein	-
EL083_RS03190	671151..672026	+	876	WP_002444902.1	citrate (pro-3S)-lyase subunit beta	-
EL083_RS03195	672037..673554	+	1518	WP_002444904.1	citrate lyase subunit alpha	-
EL083_RS03200	673559..674098	+	540	WP_002444905.1	citrate lyase holo-[acyl-carrier protein] synthase	-
EL083_RS03205	674076..674933	+	858	WP_002444907.1	triphosphoribosyl-dephospho-CoA synthase CitG	-
-	675168..675204	-	37	-	-	Antitoxin
EL083_RS03210	675268..675429	+	162	WP_014715816.1	Hok/Gef family protein	Toxin
EL083_RS03215	675836..675997	+	162	WP_071840846.1	Hok/Gef family protein	-
EL083_RS03220	676115..677200	-	1086	WP_002444912.1	membrane-bound lytic murein transglycosylase MltC	-
EL083_RS03225	677300..677572	-	273	WP_002444915.1	oxidative damage protection protein	-
EL083_RS03230	677575..678657	-	1083	WP_002444917.1	A/G-specific adenine glycosylase	-
EL083_RS03235	678814..679533	+	720	WP_002444919.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
EL083_RS03240	679533..679859	+	327	WP_002444921.1	YggL family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (8-48)

Sequences

Toxin

Protein

• Length: 54 a.a.
• Molecular weight: 5822.12 Da
• Isoelectric Point: 7.5949

>T287071 WP_014715816.1 NZ_LR134215:675268-675429 [Shimwellia blattae]
MKLSQYSAVWCLLIVCLTLLLLTLIIRPQLCEVRIIQGDREIAAIMACGSGTS

Nucleotide

• Length: 162 bp

Antitoxin

Nucleotide

• Length: 37 bp

>AT287071 NZ_LR134215:c675204-675168 [Shimwellia blattae]
GGCCTCGTGGATTAATGAAAATTAACTACGGGGCTTT

Structures

Antitoxin