Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2227540..2227757 Replicon chromosome
Accession NZ_LR134193
Organism Staphylococcus aureus strain NCTC13616

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag EL036_RS11460 Protein ID WP_075583739.1
Coordinates 2227653..2227757 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2227540..2227595 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL036_RS11440 2223596..2224261 - 666 WP_001024097.1 SDR family oxidoreductase -
EL036_RS11445 2224413..2224733 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EL036_RS11450 2224735..2225715 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
EL036_RS11455 2225981..2227072 + 1092 WP_000495678.1 hypothetical protein -
- 2227540..2227595 + 56 - - Antitoxin
EL036_RS11460 2227653..2227757 - 105 WP_075583739.1 hypothetical protein Toxin
EL036_RS11465 2227855..2228016 - 162 Protein_2137 helix-turn-helix domain-containing protein -
EL036_RS11475 2228434..2228592 + 159 WP_024928151.1 hypothetical protein -
EL036_RS11485 2229252..2230109 - 858 WP_000370944.1 Cof-type HAD-IIB family hydrolase -
EL036_RS11490 2230177..2230959 - 783 WP_000908181.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3861.73 Da        Isoelectric Point: 7.0039

>T286986 WP_075583739.1 NZ_LR134193:c2227757-2227653 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT286986 NZ_LR134193:2227540-2227595 [Staphylococcus aureus]
AAAAAGGGCAACACTCAGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References