Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1894974..1895154 Replicon chromosome
Accession NZ_LR134193
Organism Staphylococcus aureus strain NCTC13616

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag EL036_RS09400 Protein ID WP_001801861.1
Coordinates 1894974..1895069 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1895097..1895154 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL036_RS09360 1890261..1891028 - 768 WP_001095317.1 IS21-like element helper ATPase IstB -
EL036_RS09365 1891040..1892275 - 1236 WP_001215400.1 IS21 family transposase -
EL036_RS09370 1892633..1893202 - 570 WP_000864144.1 ImmA/IrrE family metallo-endopeptidase -
EL036_RS09380 1893575..1893751 - 177 WP_000375476.1 hypothetical protein -
EL036_RS09385 1893762..1894145 - 384 WP_000070809.1 hypothetical protein -
EL036_RS09390 1894327..1894551 - 225 WP_001805677.1 IS3 family transposase -
EL036_RS09395 1894725..1894829 - 105 WP_001670380.1 transposase -
EL036_RS09400 1894974..1895069 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1895097..1895154 - 58 - - Antitoxin
EL036_RS09405 1895192..1895293 + 102 WP_001791232.1 hypothetical protein -
EL036_RS09410 1895271..1895443 - 173 Protein_1786 transposase -
EL036_RS09415 1895637..1896014 - 378 WP_001036002.1 DUF1433 domain-containing protein -
EL036_RS09420 1896221..1896661 - 441 WP_000759947.1 DUF1433 domain-containing protein -
EL036_RS09425 1896706..1898319 + 1614 WP_000926708.1 lipase -
EL036_RS09430 1898334..1898633 + 300 WP_000095392.1 WXG100 family type VII secretion target -
EL036_RS09435 1898950..1900131 - 1182 WP_000162901.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - selk 1865623..1911385 45762


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T286980 WP_001801861.1 NZ_LR134193:1894974-1895069 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T286980 NZ_LR134193:1894974-1895069 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT286980 NZ_LR134193:c1895154-1895097 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References