Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-SprF3/-
Location 1524253..1524552 Replicon chromosome
Accession NZ_LR134193
Organism Staphylococcus aureus strain NCTC13616

Toxin (Protein)


Gene name txpA Uniprot ID Q2FWU9
Locus tag EL036_RS07425 Protein ID WP_011447039.1
Coordinates 1524376..1524552 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1524253..1524308 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL036_RS14670 1519487..1519702 - 216 WP_170267452.1 hypothetical protein -
EL036_RS07400 1519881..1520891 - 1011 WP_000777019.1 restriction endonuclease subunit S -
EL036_RS07405 1520878..1522782 - 1905 WP_001003363.1 N-6 DNA methylase -
EL036_RS07410 1523143..1523898 - 756 WP_000861038.1 CHAP domain-containing protein -
EL036_RS07415 1523910..1524164 - 255 WP_000611512.1 phage holin -
EL036_RS07420 1524216..1524323 + 108 WP_001791821.1 hypothetical protein -
- 1524245..1524384 + 140 NuclAT_0 - -
- 1524245..1524384 + 140 NuclAT_0 - -
- 1524245..1524384 + 140 NuclAT_0 - -
- 1524245..1524384 + 140 NuclAT_0 - -
- 1524253..1524308 + 56 - - Antitoxin
EL036_RS07425 1524376..1524552 - 177 WP_011447039.1 putative holin-like toxin Toxin
EL036_RS07430 1524705..1525004 - 300 WP_000466784.1 DUF2951 domain-containing protein -
EL036_RS07435 1525050..1525214 - 165 WP_000916020.1 XkdX family protein -
EL036_RS07440 1525207..1525596 - 390 WP_001166596.1 DUF2977 domain-containing protein -
EL036_RS07445 1525596..1527062 - 1467 WP_000067127.1 BppU family phage baseplate upper protein -
EL036_RS07450 1527062..1528972 - 1911 WP_000429558.1 minor structural protein -
EL036_RS07455 1528988..1529278 - 291 WP_000179858.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1515948..1580722 64774


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(30-58)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6849.45 Da        Isoelectric Point: 10.6777

>T286976 WP_011447039.1 NZ_LR134193:c1524552-1524376 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Download         Length: 177 bp

Antitoxin


Download         Length: 56 bp

>AT286976 NZ_LR134193:1524253-1524308 [Staphylococcus aureus]
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 7NS1

Antitoxin

Download structure file

References