Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 1554730..1555379 Replicon chromosome
Accession NZ_LR134167
Organism Avibacterium volantium strain NCTC3438

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag ELZ61_RS07485 Protein ID WP_126372598.1
Coordinates 1555047..1555379 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag ELZ61_RS07480 Protein ID WP_126372596.1
Coordinates 1554730..1555044 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ61_RS07470 1550638..1552497 + 1860 WP_126372592.1 1-deoxy-D-xylulose-5-phosphate synthase -
ELZ61_RS07475 1552683..1554626 - 1944 WP_126372594.1 ABC transporter ATP-binding protein -
ELZ61_RS07480 1554730..1555044 - 315 WP_126372596.1 helix-turn-helix domain-containing protein Antitoxin
ELZ61_RS07485 1555047..1555379 - 333 WP_126372598.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ELZ61_RS07490 1555455..1555979 - 525 WP_126372600.1 gluconokinase -
ELZ61_RS07495 1556258..1557607 + 1350 WP_126372602.1 GntP family permease -
ELZ61_RS07505 1558194..1559111 - 918 WP_164550727.1 mechanosensitive ion channel -
ELZ61_RS07510 1559187..1560254 - 1068 WP_126372606.1 LPS export ABC transporter permease LptG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(10-104)

Antitoxin

Cro/C1-type helix-turn-helix domain

(45-82)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12787.87 Da        Isoelectric Point: 9.7722

>T286939 WP_126372598.1 NZ_LR134167:c1555379-1555047 [Avibacterium volantium]
MKAVFIELPFFEKYRKEYLSDDEYLMLQNELLVTPEKGDLIQGTGGLRKLRIANSKRNRGKRGGARVIYYYYVHNAAIYF
LTAYGKEMKEDLTADEKSILVKIVENIKGK

Download         Length: 333 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11994.84 Da        Isoelectric Point: 8.5686

>AT286939 WP_126372596.1 NZ_LR134167:c1555044-1554730 [Avibacterium volantium]
MERNLFEELKQGLEQMQAHLEGKTTLKTIERELPAEMGEISANEVKSIREKLNLSQSVFAKKLRMSVRTYQGWEQGKTTP
NKQATLLLKMIERSPQTFEEIASL

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References