Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2446783..2446967 Replicon chromosome
Accession NZ_LR134139
Organism Staphylococcus aureus strain NCTC4163

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag ELZ55_RS12825 Protein ID WP_000482647.1
Coordinates 2446860..2446967 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2446783..2446843 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ55_RS12800 2442237..2442404 - 168 WP_001790576.1 hypothetical protein -
ELZ55_RS12810 2442635..2444368 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
ELZ55_RS12815 2444393..2446156 - 1764 WP_001064814.1 ABC transporter ATP-binding protein/permease -
- 2446783..2446843 + 61 - - Antitoxin
ELZ55_RS12825 2446860..2446967 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
ELZ55_RS12830 2447101..2447487 - 387 WP_000779360.1 flippase GtxA -
ELZ55_RS12835 2447745..2448887 + 1143 WP_042727740.1 glycerate kinase -
ELZ55_RS12840 2448947..2449606 + 660 WP_000831298.1 membrane protein -
ELZ55_RS12845 2449788..2450999 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
ELZ55_RS12850 2451122..2451595 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T286854 WP_000482647.1 NZ_LR134139:c2446967-2446860 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT286854 NZ_LR134139:2446783-2446843 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACTAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References