Detailed information of TA system TA286849

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-SprF3/-
• Location: 1988711..1989010
• Replicon: chromosome
• Accession: NZ_LR134139
• Organism: Staphylococcus aureus strain NCTC4163

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: ELZ55_RS10250
• Protein ID: WP_072353918.1
• Coordinates: 1988834..1989010 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	1988711..1988766 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ELZ55_RS10195	1984269..1984448	+	180	WP_000669789.1	hypothetical protein	-
ELZ55_RS10205	1984759..1985019	+	261	WP_001791826.1	hypothetical protein	-
ELZ55_RS10210	1985072..1985422	-	351	WP_000702262.1	complement inhibitor SCIN-A	-
ELZ55_RS10215	1985932..1986267	-	336	Protein_1877	SH3 domain-containing protein	-
ELZ55_RS10230	1986919..1987410	-	492	WP_000920041.1	staphylokinase	-
ELZ55_RS10235	1987601..1988356	-	756	WP_000861038.1	CHAP domain-containing protein	-
ELZ55_RS10240	1988368..1988622	-	255	WP_000611512.1	phage holin	-
ELZ55_RS10245	1988674..1988781	+	108	WP_001791821.1	hypothetical protein	-
-	1988703..1988842	+	140	NuclAT_0	-	-
-	1988703..1988842	+	140	NuclAT_0	-	-
-	1988703..1988842	+	140	NuclAT_0	-	-
-	1988703..1988842	+	140	NuclAT_0	-	-
-	1988711..1988766	+	56	-	-	Antitoxin
ELZ55_RS10250	1988834..1989010	-	177	WP_072353918.1	putative holin-like toxin	Toxin
ELZ55_RS10255	1989153..1989527	-	375	WP_000340977.1	hypothetical protein	-
ELZ55_RS10260	1989583..1989870	-	288	WP_001262620.1	hypothetical protein	-
ELZ55_RS10265	1989916..1990068	-	153	WP_001000058.1	hypothetical protein	-
ELZ55_RS10270	1990061..1993843	-	3783	WP_042727565.1	phage minor structural protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	scn / sak / hlb / groEL	1985072..2039678	54606

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (30-58)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6810.43 Da
• Isoelectric Point: 9.9479

>T286849 WP_072353918.1 NZ_LR134139:c1989010-1988834 [Staphylococcus aureus]
MDRWWLSEYKEVVPMLALLKSLERRCLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Nucleotide

• Length: 177 bp

Antitoxin

Nucleotide

• Length: 56 bp

>AT286849 NZ_LR134139:1988711-1988766 [Staphylococcus aureus]
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin