Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2531792..2531976 Replicon chromosome
Accession NZ_LR134093
Organism Staphylococcus aureus strain NCTC11965

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag ELZ56_RS13060 Protein ID WP_000482647.1
Coordinates 2531869..2531976 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2531792..2531852 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ56_RS13035 2527302..2527469 - 168 Protein_2418 hypothetical protein -
ELZ56_RS13045 2527700..2529433 - 1734 WP_000486505.1 ABC transporter ATP-binding protein/permease -
ELZ56_RS13050 2529458..2531221 - 1764 WP_001064829.1 ABC transporter ATP-binding protein/permease -
- 2531792..2531852 + 61 - - Antitoxin
ELZ56_RS13060 2531869..2531976 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
ELZ56_RS13065 2532110..2532496 - 387 WP_000779351.1 flippase GtxA -
ELZ56_RS13070 2532764..2533906 + 1143 WP_001176855.1 glycerate kinase -
ELZ56_RS13075 2533966..2534625 + 660 WP_000831298.1 membrane protein -
ELZ56_RS13080 2534807..2536018 + 1212 WP_001191919.1 multidrug effflux MFS transporter -
ELZ56_RS13085 2536141..2536614 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T286794 WP_000482647.1 NZ_LR134093:c2531976-2531869 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT286794 NZ_LR134093:2531792-2531852 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References