Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2242227..2242443 Replicon chromosome
Accession NZ_LR134093
Organism Staphylococcus aureus strain NCTC11965

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag ELZ56_RS11485 Protein ID WP_073392962.1
Coordinates 2242339..2242443 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2242227..2242282 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ56_RS11465 2237320..2237640 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ELZ56_RS11470 2237642..2238622 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
ELZ56_RS11475 2238888..2239979 + 1092 WP_000495684.1 hypothetical protein -
ELZ56_RS11480 2240267..2241913 + 1647 WP_000277709.1 IS1182-like element ISSau3 family transposase -
- 2242227..2242282 + 56 - - Antitoxin
ELZ56_RS11485 2242339..2242443 - 105 WP_073392962.1 hypothetical protein Toxin
ELZ56_RS11495 2243123..2243281 + 159 WP_001792784.1 hypothetical protein -
ELZ56_RS11505 2243940..2244797 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
ELZ56_RS11510 2244865..2245647 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2240267..2241913 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T286791 WP_073392962.1 NZ_LR134093:c2242443-2242339 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp


Antitoxin


Download         Length: 56 bp

>AT286791 NZ_LR134093:2242227-2242282 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References