Detailed information of TA system TA286791

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2242227..2242443
• Replicon: chromosome
• Accession: NZ_LR134093
• Organism: Staphylococcus aureus strain NCTC11965

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: ELZ56_RS11485
• Protein ID: WP_073392962.1
• Coordinates: 2242339..2242443 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2242227..2242282 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ELZ56_RS11465	2237320..2237640	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
ELZ56_RS11470	2237642..2238622	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
ELZ56_RS11475	2238888..2239979	+	1092	WP_000495684.1	hypothetical protein	-
ELZ56_RS11480	2240267..2241913	+	1647	WP_000277709.1	IS1182-like element ISSau3 family transposase	-
-	2242227..2242282	+	56	-	-	Antitoxin
ELZ56_RS11485	2242339..2242443	-	105	WP_073392962.1	hypothetical protein	Toxin
ELZ56_RS11495	2243123..2243281	+	159	WP_001792784.1	hypothetical protein	-
ELZ56_RS11505	2243940..2244797	-	858	WP_000370937.1	Cof-type HAD-IIB family hydrolase	-
ELZ56_RS11510	2244865..2245647	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2240267..2241913	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T286791 WP_073392962.1 NZ_LR134093:c2242443-2242339 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 56 bp

>AT286791 NZ_LR134093:2242227-2242282 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin