Detailed information of TA system TA286783

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1889889..1890069
• Replicon: chromosome
• Accession: NZ_LR134093
• Organism: Staphylococcus aureus strain NCTC11965

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: ELZ56_RS09330
• Protein ID: WP_001801861.1
• Coordinates: 1889889..1889984 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1890012..1890069 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ELZ56_RS09295	1885033..1885659	+	627	WP_000669038.1	hypothetical protein	-
ELZ56_RS09300	1885700..1886044	+	345	WP_000627550.1	DUF3969 family protein	-
ELZ56_RS09305	1886142..1886714	+	573	WP_000414222.1	hypothetical protein	-
ELZ56_RS09310	1886863..1888230	-	1368	WP_001093574.1	FRG domain-containing protein	-
ELZ56_RS09315	1888230..1888799	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
ELZ56_RS09320	1888992..1889438	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
ELZ56_RS09330	1889889..1889984	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1890012..1890069	-	58	-	-	Antitoxin
ELZ56_RS09335	1890107..1890208	+	102	WP_001791232.1	hypothetical protein	-
ELZ56_RS09340	1890383..1890826	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
ELZ56_RS09345	1890826..1891269	-	444	WP_115307081.1	DUF1433 domain-containing protein	-
ELZ56_RS09350	1891269..1891711	-	443	Protein_1762	DUF1433 domain-containing protein	-
ELZ56_RS09355	1892236..1894656	+	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T286783 WP_001801861.1 NZ_LR134093:1889889-1889984 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 58 bp

>AT286783 NZ_LR134093:c1890069-1890012 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin