Detailed information of TA system TA286782

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1016682..1016931
• Replicon: chromosome
• Accession: NZ_LR134093
• Organism: Staphylococcus aureus strain NCTC11965

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: ELZ56_RS05035
• Protein ID: WP_000623369.1
• Coordinates: 1016682..1016789 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1016784..1016931 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ELZ56_RS05010	1013355..1013924	-	570	WP_000287265.1	competence protein ComK	-
ELZ56_RS05015	1014134..1014352	+	219	WP_000876825.1	IDEAL domain-containing protein	-
ELZ56_RS05020	1014433..1015419	-	987	WP_000668820.1	lipoate--protein ligase	-
ELZ56_RS05025	1015618..1015794	+	177	WP_000214898.1	YkvS family protein	-
ELZ56_RS05030	1015809..1016411	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
ELZ56_RS05035	1016682..1016789	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	1016784..1016931	-	148	-	-	Antitoxin
ELZ56_RS05040	1017328..1017429	+	102	WP_001790623.1	hypothetical protein	-
ELZ56_RS05045	1017439..1017711	+	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
ELZ56_RS05050	1017755..1019719	+	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
ELZ56_RS05055	1019722..1020042	+	321	WP_000873929.1	YxeA family protein	-
ELZ56_RS05060	1020039..1020680	+	642	WP_000571191.1	ABC transporter ATP-binding protein	-
ELZ56_RS05065	1020768..1021058	-	291	WP_001791476.1	hypothetical protein	-
ELZ56_RS05070	1021399..1021686	+	288	WP_000410718.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T286782 WP_000623369.1 NZ_LR134093:1016682-1016789 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 148 bp

>AT286782 NZ_LR134093:c1016931-1016784 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGGAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTTCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin