Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2436399..2436583 Replicon chromosome
Accession NZ_LR134091
Organism Staphylococcus aureus strain NCTC4137

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag ELZ58_RS12695 Protein ID WP_000482647.1
Coordinates 2436476..2436583 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2436399..2436459 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ58_RS12670 2431853..2432020 - 168 WP_001790576.1 hypothetical protein -
ELZ58_RS12680 2432251..2433984 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
ELZ58_RS12685 2434009..2435772 - 1764 WP_001064814.1 ABC transporter ATP-binding protein/permease -
- 2436399..2436459 + 61 - - Antitoxin
ELZ58_RS12695 2436476..2436583 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
ELZ58_RS12700 2436717..2437103 - 387 WP_000779360.1 flippase GtxA -
ELZ58_RS12705 2437361..2438503 + 1143 WP_042727740.1 glycerate kinase -
ELZ58_RS12710 2438563..2439222 + 660 WP_000831298.1 membrane protein -
ELZ58_RS12715 2439404..2440615 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
ELZ58_RS12720 2440738..2441211 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T286753 WP_000482647.1 NZ_LR134091:c2436583-2436476 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT286753 NZ_LR134091:2436399-2436459 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References