Detailed information of TA system TA286747

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-SprF1/-
• Location: 1979717..1980024
• Replicon: chromosome
• Accession: NZ_LR134091
• Organism: Staphylococcus aureus strain NCTC4137

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: ELZ58_RS10130
• Protein ID: WP_072353918.1
• Coordinates: 1979848..1980024 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1979717..1979856 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ELZ58_RS10075	1975283..1975462	+	180	WP_000669789.1	hypothetical protein	-
ELZ58_RS10085	1975773..1976033	+	261	WP_001791826.1	hypothetical protein	-
ELZ58_RS10090	1976086..1976436	-	351	WP_000702262.1	complement inhibitor SCIN-A	-
ELZ58_RS10095	1976946..1977281	-	336	Protein_1858	SH3 domain-containing protein	-
ELZ58_RS10110	1977933..1978424	-	492	WP_000920041.1	staphylokinase	-
ELZ58_RS10115	1978615..1979370	-	756	WP_000861038.1	CHAP domain-containing protein	-
ELZ58_RS10120	1979382..1979636	-	255	WP_000611512.1	phage holin	-
ELZ58_RS10125	1979688..1979795	+	108	WP_001791821.1	hypothetical protein	-
-	1979717..1979856	+	140	NuclAT_0	-	Antitoxin
-	1979717..1979856	+	140	NuclAT_0	-	Antitoxin
-	1979717..1979856	+	140	NuclAT_0	-	Antitoxin
-	1979717..1979856	+	140	NuclAT_0	-	Antitoxin
ELZ58_RS10130	1979848..1980024	-	177	WP_072353918.1	putative holin-like toxin	Toxin
ELZ58_RS10135	1980167..1980541	-	375	WP_000340977.1	hypothetical protein	-
ELZ58_RS10140	1980597..1980884	-	288	WP_001262620.1	hypothetical protein	-
ELZ58_RS10145	1980930..1981082	-	153	WP_001000058.1	hypothetical protein	-
ELZ58_RS10150	1981075..1984857	-	3783	WP_001836550.1	phage protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	scn / sak / hlb / groEL	1976086..2030692	54606

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (30-58)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6810.43 Da
• Isoelectric Point: 9.9479

>T286747 WP_072353918.1 NZ_LR134091:c1980024-1979848 [Staphylococcus aureus]
MDRWWLSEYKEVVPMLALLKSLERRCLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Nucleotide

• Length: 177 bp

Antitoxin

Nucleotide

• Length: 140 bp

>AT286747 NZ_LR134091:1979717-1979856 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT

Structures

Antitoxin