Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2245241..2245439 Replicon chromosome
Accession NZ_LR134090
Organism Staphylococcus aureus strain NCTC9555

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag ELZ60_RS11775 Protein ID WP_001802298.1
Coordinates 2245335..2245439 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2245241..2245279 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ60_RS11755 2241350..2242015 - 666 WP_001024100.1 SDR family oxidoreductase -
ELZ60_RS11760 2242167..2242487 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ELZ60_RS11765 2242489..2243469 + 981 WP_000019740.1 CDF family zinc efflux transporter CzrB -
ELZ60_RS11770 2243735..2244826 + 1092 WP_000495692.1 hypothetical protein -
- 2245241..2245279 + 39 - - Antitoxin
ELZ60_RS11775 2245335..2245439 - 105 WP_001802298.1 hypothetical protein Toxin
ELZ60_RS14865 2245600..2246083 - 484 Protein_2172 recombinase family protein -
ELZ60_RS11785 2246126..2247246 - 1121 Protein_2173 SAP domain-containing protein -
ELZ60_RS11790 2248295..2249152 - 858 WP_000370943.1 Cof-type HAD-IIB family hydrolase -
ELZ60_RS11795 2249220..2250002 - 783 WP_000909235.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T286742 WP_001802298.1 NZ_LR134090:c2245439-2245335 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT286742 NZ_LR134090:2245241-2245279 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References