Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2600638..2600795 Replicon chromosome
Accession NZ_LR134089
Organism Staphylococcus saprophyticus strain NCTC7666

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag ELZ48_RS12685 Protein ID WP_002441941.1
Coordinates 2600700..2600795 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2600638..2600671 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ48_RS12660 2595645..2596478 + 834 WP_041080289.1 aldo/keto reductase -
ELZ48_RS12665 2596945..2597244 - 300 WP_011304021.1 hypothetical protein -
ELZ48_RS12670 2597620..2597856 + 237 WP_115338747.1 ferrous iron transport protein A -
ELZ48_RS12675 2597849..2599843 + 1995 WP_126424559.1 ferrous iron transport protein B -
ELZ48_RS12680 2599856..2600011 + 156 WP_075340076.1 FeoB-associated Cys-rich membrane protein -
ELZ48_RS12845 2600256..2600393 + 138 WP_002484366.1 hypothetical protein -
- 2600638..2600671 + 34 - - Antitoxin
ELZ48_RS12685 2600700..2600795 - 96 WP_002441941.1 type I toxin-antitoxin system Fst family toxin Toxin
ELZ48_RS12690 2601098..2601856 - 759 WP_002484367.1 MerR family transcriptional regulator -
ELZ48_RS12695 2601966..2602529 - 564 WP_126424560.1 helix-turn-helix domain-containing protein -
ELZ48_RS12700 2602723..2604180 - 1458 WP_126424561.1 carbon starvation protein A -
ELZ48_RS12705 2604388..2605227 - 840 WP_002481957.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3560.34 Da        Isoelectric Point: 9.9256

>T286731 WP_002441941.1 NZ_LR134089:c2600795-2600700 [Staphylococcus saprophyticus]
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK

Download         Length: 96 bp


Antitoxin


Download         Length: 34 bp

>AT286731 NZ_LR134089:2600638-2600671 [Staphylococcus saprophyticus]
CACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References