Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2519647..2519831 Replicon chromosome
Accession NZ_LR134087
Organism Staphylococcus aureus strain NCTC7121

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag ELZ50_RS13200 Protein ID WP_000482647.1
Coordinates 2519724..2519831 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2519647..2519707 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ50_RS13175 2515101..2515268 - 168 WP_001790576.1 hypothetical protein -
ELZ50_RS13185 2515499..2517232 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
ELZ50_RS13190 2517257..2519020 - 1764 WP_001064814.1 ABC transporter ATP-binding protein/permease -
- 2519647..2519707 + 61 - - Antitoxin
ELZ50_RS13200 2519724..2519831 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
ELZ50_RS13205 2519965..2520351 - 387 WP_000779360.1 flippase GtxA -
ELZ50_RS13210 2520609..2521751 + 1143 WP_001176863.1 glycerate kinase -
ELZ50_RS13215 2521811..2522470 + 660 WP_000831298.1 membrane protein -
ELZ50_RS13220 2522652..2523863 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
ELZ50_RS13225 2523986..2524459 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T286726 WP_000482647.1 NZ_LR134087:c2519831-2519724 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT286726 NZ_LR134087:2519647-2519707 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References