286716

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2525858..2526042 Replicon chromosome
Accession NZ_LR134086
Organism Staphylococcus aureus strain NCTC13142

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag ELZ49_RS13095 Protein ID WP_000482647.1
Coordinates 2525935..2526042 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2525858..2525918 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ49_RS13085 2521654..2523387 - 1734 WP_000486501.1 ABC transporter ATP-binding protein/permease -
ELZ49_RS13090 2523412..2525175 - 1764 WP_001064811.1 ABC transporter ATP-binding protein/permease -
- 2525858..2525918 + 61 - - Antitoxin
ELZ49_RS13095 2525935..2526042 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
ELZ49_RS13100 2526176..2526562 - 387 WP_000779356.1 flippase GtxA -
ELZ49_RS13105 2526830..2527972 + 1143 WP_001176863.1 glycerate kinase -
ELZ49_RS13110 2528032..2528691 + 660 WP_000831298.1 membrane protein -
ELZ49_RS13115 2528870..2530081 + 1212 WP_001191976.1 multidrug effflux MFS transporter -
ELZ49_RS13120 2530204..2530677 - 474 WP_000456498.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T286716 WP_000482647.1 NZ_LR134086:c2526042-2525935 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT286716 NZ_LR134086:2525858-2525918 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References