Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2239026..2239243 Replicon chromosome
Accession NZ_LR134086
Organism Staphylococcus aureus strain NCTC13142

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag ELZ49_RS11550 Protein ID WP_075583739.1
Coordinates 2239139..2239243 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2239026..2239081 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ49_RS11530 2235148..2235813 - 666 WP_001024097.1 SDR family oxidoreductase -
ELZ49_RS11535 2235965..2236285 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ELZ49_RS11540 2236287..2237267 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
ELZ49_RS11545 2237533..2238624 + 1092 WP_000495678.1 hypothetical protein -
- 2239026..2239081 + 56 - - Antitoxin
ELZ49_RS11550 2239139..2239243 - 105 WP_075583739.1 hypothetical protein Toxin
ELZ49_RS11555 2239341..2239502 - 162 Protein_2151 helix-turn-helix domain-containing protein -
ELZ49_RS11565 2239920..2240078 + 159 WP_024928151.1 hypothetical protein -
ELZ49_RS11575 2240738..2241595 - 858 WP_000370944.1 Cof-type HAD-IIB family hydrolase -
ELZ49_RS11580 2241663..2242445 - 783 WP_000908181.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3861.73 Da        Isoelectric Point: 7.0039

>T286713 WP_075583739.1 NZ_LR134086:c2239243-2239139 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT286713 NZ_LR134086:2239026-2239081 [Staphylococcus aureus]
AAAAAGGGCAACACTCAGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References