Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2238971..2239188 Replicon chromosome
Accession NZ_LR134085
Organism Staphylococcus aureus strain NCTC12233

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag ELZ52_RS11750 Protein ID WP_001802298.1
Coordinates 2239084..2239188 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2238971..2239026 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ52_RS11730 2235108..2235773 - 666 WP_045177733.1 SDR family oxidoreductase -
ELZ52_RS11735 2235925..2236245 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ELZ52_RS11740 2236247..2237227 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
ELZ52_RS11745 2237493..2238584 + 1092 WP_000495671.1 lytic regulatory protein -
ELZ52_RS11750 2239084..2239188 - 105 WP_001802298.1 hypothetical protein Toxin
ELZ52_RS14965 2239349..2239832 - 484 Protein_2163 recombinase family protein -
ELZ52_RS11760 2239875..2241011 - 1137 WP_000115564.1 SAP domain-containing protein -
ELZ52_RS11765 2241300..2241392 + 93 WP_001790138.1 hypothetical protein -
ELZ52_RS11770 2242097..2242954 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
ELZ52_RS11775 2243022..2243804 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T286697 WP_001802298.1 NZ_LR134085:c2239188-2239084 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT286697 NZ_LR134085:2238971-2239026 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References