Detailed information of TA system TA286579

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 188762..188984
• Replicon: chromosome
• Accession: NZ_LR134031
• Organism: Escherichia coli strain NCTC11151

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: A0A0D6GD35
• Locus tag: EL024_RS00905
• Protein ID: WP_000170745.1
• Coordinates: 188877..188984 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	188762..188820 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EL024_RS00880	184203..185105	+	903	WP_000084677.1	dipeptide ABC transporter permease DppC	-
EL024_RS00885	185116..186099	+	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-
EL024_RS00890	186096..187100	+	1005	WP_000103579.1	dipeptide ABC transporter ATP-binding subunit DppF	-
EL024_RS00895	187130..188401	-	1272	WP_001332306.1	amino acid permease	-
-	188762..188820	-	59	-	-	Antitoxin
EL024_RS00905	188877..188984	+	108	WP_000170745.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
EL024_RS00910	189359..189466	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
EL024_RS00920	189842..189949	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
EL024_RS00925	190035..191714	-	1680	WP_000191567.1	cellulose biosynthesis protein BcsG	-
EL024_RS00930	191711..191902	-	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
EL024_RS00935	191899..193470	-	1572	WP_001204957.1	cellulose biosynthesis protein BcsE	-
EL024_RS00940	193743..193931	+	189	WP_001063314.1	YhjR family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3855.68 Da
• Isoelectric Point: 9.0157

>T286579 WP_000170745.1 NZ_LR134031:188877-188984 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVSWLNKRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 59 bp

>AT286579 NZ_LR134031:c188820-188762 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A0D6GD35

Antitoxin