286517

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2438508..2438692 Replicon chromosome
Accession NZ_LR133917
Organism Staphylococcus aureus strain NCTC8317

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag ELZ45_RS12680 Protein ID WP_000482652.1
Coordinates 2438585..2438692 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2438508..2438568 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ45_RS12655 2434019..2434186 - 168 Protein_2343 hypothetical protein -
ELZ45_RS12665 2434417..2436150 - 1734 WP_031918671.1 ABC transporter ATP-binding protein/permease -
ELZ45_RS12670 2436175..2437938 - 1764 WP_001064809.1 ABC transporter ATP-binding protein/permease -
- 2438508..2438568 + 61 - - Antitoxin
ELZ45_RS12680 2438585..2438692 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
ELZ45_RS12685 2438826..2439212 - 387 WP_000779357.1 flippase GtxA -
ELZ45_RS12690 2439480..2440622 + 1143 WP_001176863.1 glycerate kinase -
ELZ45_RS12695 2440682..2441341 + 660 WP_000831298.1 membrane protein -
ELZ45_RS12700 2441523..2442734 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
ELZ45_RS12705 2442857..2443330 - 474 WP_000456484.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T286517 WP_000482652.1 NZ_LR133917:c2438692-2438585 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT286517 NZ_LR133917:2438508-2438568 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References