Detailed information of TA system TA286507

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1817771..1817951
• Replicon: chromosome
• Accession: NZ_LR133917
• Organism: Staphylococcus aureus strain NCTC8317

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: ELZ45_RS09040
• Protein ID: WP_001801861.1
• Coordinates: 1817771..1817866 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1817894..1817951 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ELZ45_RS09010	1812933..1813583	+	651	WP_072470537.1	excalibur calcium-binding domain-containing protein	-
ELZ45_RS09015	1813664..1814659	+	996	WP_000070641.1	DUF4352 domain-containing protein	-
ELZ45_RS09020	1814734..1815360	+	627	WP_000669026.1	hypothetical protein	-
ELZ45_RS09025	1815401..1815742	+	342	WP_000627537.1	DUF3969 family protein	-
ELZ45_RS09030	1815843..1816415	+	573	WP_000414215.1	hypothetical protein	-
ELZ45_RS09035	1816614..1817626	-	1013	Protein_1700	IS3 family transposase	-
ELZ45_RS09040	1817771..1817866	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1817894..1817951	-	58	-	-	Antitoxin
ELZ45_RS09045	1817989..1818090	+	102	WP_001792025.1	hypothetical protein	-
ELZ45_RS09050	1818068..1818229	-	162	Protein_1703	transposase	-
ELZ45_RS09055	1818220..1818714	-	495	Protein_1704	transposase	-
ELZ45_RS09060	1819166..1820395	-	1230	WP_061826460.1	restriction endonuclease subunit S	-
ELZ45_RS09065	1820388..1821944	-	1557	WP_094360170.1	type I restriction-modification system subunit M	-
ELZ45_RS09070	1822109..1822243	-	135	Protein_1707	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	1812175..1853340	41165

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T286507 WP_001801861.1 NZ_LR133917:1817771-1817866 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 58 bp

>AT286507 NZ_LR133917:c1817951-1817894 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin