Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 2078277..2078498 Replicon chromosome
Accession NZ_LR130532
Organism Escherichia coli isolate ecoli019

Toxin (Protein)


Gene name ldrD Uniprot ID S1PGT3
Locus tag EJK95_RS10025 Protein ID WP_000170954.1
Coordinates 2078277..2078384 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 2078432..2078498 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJK95_RS10000 2074121..2075203 + 1083 WP_000804726.1 peptide chain release factor 1 -
EJK95_RS10005 2075203..2076036 + 834 WP_000456571.1 peptide chain release factor N(5)-glutamine methyltransferase -
EJK95_RS10010 2076033..2076425 + 393 WP_000200392.1 invasion regulator SirB2 -
EJK95_RS10015 2076429..2077238 + 810 WP_001257044.1 invasion regulator SirB1 -
EJK95_RS10020 2077274..2078128 + 855 WP_000811065.1 3-deoxy-8-phosphooctulonate synthase -
EJK95_RS10025 2078277..2078384 - 108 WP_000170954.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 2078432..2078498 + 67 NuclAT_26 - Antitoxin
- 2078432..2078498 + 67 NuclAT_26 - Antitoxin
- 2078432..2078498 + 67 NuclAT_26 - Antitoxin
- 2078432..2078498 + 67 NuclAT_26 - Antitoxin
- 2078432..2078498 + 67 NuclAT_28 - Antitoxin
- 2078432..2078498 + 67 NuclAT_28 - Antitoxin
- 2078432..2078498 + 67 NuclAT_28 - Antitoxin
- 2078432..2078498 + 67 NuclAT_28 - Antitoxin
- 2078432..2078498 + 67 NuclAT_30 - Antitoxin
- 2078432..2078498 + 67 NuclAT_30 - Antitoxin
- 2078432..2078498 + 67 NuclAT_30 - Antitoxin
- 2078432..2078498 + 67 NuclAT_30 - Antitoxin
- 2078432..2078498 + 67 NuclAT_32 - Antitoxin
- 2078432..2078498 + 67 NuclAT_32 - Antitoxin
- 2078432..2078498 + 67 NuclAT_32 - Antitoxin
- 2078432..2078498 + 67 NuclAT_32 - Antitoxin
- 2078432..2078498 + 67 NuclAT_34 - Antitoxin
- 2078432..2078498 + 67 NuclAT_34 - Antitoxin
- 2078432..2078498 + 67 NuclAT_34 - Antitoxin
- 2078432..2078498 + 67 NuclAT_34 - Antitoxin
- 2078432..2078498 + 67 NuclAT_36 - Antitoxin
- 2078432..2078498 + 67 NuclAT_36 - Antitoxin
- 2078432..2078498 + 67 NuclAT_36 - Antitoxin
- 2078432..2078498 + 67 NuclAT_36 - Antitoxin
- 2078434..2078497 + 64 NuclAT_39 - -
- 2078434..2078497 + 64 NuclAT_39 - -
- 2078434..2078497 + 64 NuclAT_39 - -
- 2078434..2078497 + 64 NuclAT_39 - -
- 2078434..2078497 + 64 NuclAT_41 - -
- 2078434..2078497 + 64 NuclAT_41 - -
- 2078434..2078497 + 64 NuclAT_41 - -
- 2078434..2078497 + 64 NuclAT_41 - -
- 2078434..2078497 + 64 NuclAT_43 - -
- 2078434..2078497 + 64 NuclAT_43 - -
- 2078434..2078497 + 64 NuclAT_43 - -
- 2078434..2078497 + 64 NuclAT_43 - -
EJK95_RS10030 2078812..2078919 - 108 WP_000170926.1 type I toxin-antitoxin system toxin Ldr family protein -
- 2078972..2079033 + 62 NuclAT_38 - -
- 2078972..2079033 + 62 NuclAT_38 - -
- 2078972..2079033 + 62 NuclAT_38 - -
- 2078972..2079033 + 62 NuclAT_38 - -
- 2078972..2079033 + 62 NuclAT_40 - -
- 2078972..2079033 + 62 NuclAT_40 - -
- 2078972..2079033 + 62 NuclAT_40 - -
- 2078972..2079033 + 62 NuclAT_40 - -
- 2078972..2079033 + 62 NuclAT_42 - -
- 2078972..2079033 + 62 NuclAT_42 - -
- 2078972..2079033 + 62 NuclAT_42 - -
- 2078972..2079033 + 62 NuclAT_42 - -
- 2078972..2079034 + 63 NuclAT_27 - -
- 2078972..2079034 + 63 NuclAT_27 - -
- 2078972..2079034 + 63 NuclAT_27 - -
- 2078972..2079034 + 63 NuclAT_27 - -
- 2078972..2079034 + 63 NuclAT_29 - -
- 2078972..2079034 + 63 NuclAT_29 - -
- 2078972..2079034 + 63 NuclAT_29 - -
- 2078972..2079034 + 63 NuclAT_29 - -
- 2078972..2079034 + 63 NuclAT_31 - -
- 2078972..2079034 + 63 NuclAT_31 - -
- 2078972..2079034 + 63 NuclAT_31 - -
- 2078972..2079034 + 63 NuclAT_31 - -
- 2078972..2079034 + 63 NuclAT_33 - -
- 2078972..2079034 + 63 NuclAT_33 - -
- 2078972..2079034 + 63 NuclAT_33 - -
- 2078972..2079034 + 63 NuclAT_33 - -
- 2078972..2079034 + 63 NuclAT_35 - -
- 2078972..2079034 + 63 NuclAT_35 - -
- 2078972..2079034 + 63 NuclAT_35 - -
- 2078972..2079034 + 63 NuclAT_35 - -
- 2078972..2079034 + 63 NuclAT_37 - -
- 2078972..2079034 + 63 NuclAT_37 - -
- 2078972..2079034 + 63 NuclAT_37 - -
- 2078972..2079034 + 63 NuclAT_37 - -
- 2078972..2079035 + 64 NuclAT_15 - -
- 2078972..2079035 + 64 NuclAT_15 - -
- 2078972..2079035 + 64 NuclAT_15 - -
- 2078972..2079035 + 64 NuclAT_15 - -
- 2078972..2079035 + 64 NuclAT_17 - -
- 2078972..2079035 + 64 NuclAT_17 - -
- 2078972..2079035 + 64 NuclAT_17 - -
- 2078972..2079035 + 64 NuclAT_17 - -
- 2078972..2079035 + 64 NuclAT_19 - -
- 2078972..2079035 + 64 NuclAT_19 - -
- 2078972..2079035 + 64 NuclAT_19 - -
- 2078972..2079035 + 64 NuclAT_19 - -
- 2078972..2079035 + 64 NuclAT_21 - -
- 2078972..2079035 + 64 NuclAT_21 - -
- 2078972..2079035 + 64 NuclAT_21 - -
- 2078972..2079035 + 64 NuclAT_21 - -
- 2078972..2079035 + 64 NuclAT_23 - -
- 2078972..2079035 + 64 NuclAT_23 - -
- 2078972..2079035 + 64 NuclAT_23 - -
- 2078972..2079035 + 64 NuclAT_23 - -
- 2078972..2079035 + 64 NuclAT_25 - -
- 2078972..2079035 + 64 NuclAT_25 - -
- 2078972..2079035 + 64 NuclAT_25 - -
- 2078972..2079035 + 64 NuclAT_25 - -
EJK95_RS10035 2079348..2079455 - 108 WP_000170965.1 type I toxin-antitoxin system toxin Ldr family protein -
- 2079503..2079570 + 68 NuclAT_14 - -
- 2079503..2079570 + 68 NuclAT_14 - -
- 2079503..2079570 + 68 NuclAT_14 - -
- 2079503..2079570 + 68 NuclAT_14 - -
- 2079503..2079570 + 68 NuclAT_16 - -
- 2079503..2079570 + 68 NuclAT_16 - -
- 2079503..2079570 + 68 NuclAT_16 - -
- 2079503..2079570 + 68 NuclAT_16 - -
- 2079503..2079570 + 68 NuclAT_18 - -
- 2079503..2079570 + 68 NuclAT_18 - -
- 2079503..2079570 + 68 NuclAT_18 - -
- 2079503..2079570 + 68 NuclAT_18 - -
- 2079503..2079570 + 68 NuclAT_20 - -
- 2079503..2079570 + 68 NuclAT_20 - -
- 2079503..2079570 + 68 NuclAT_20 - -
- 2079503..2079570 + 68 NuclAT_20 - -
- 2079503..2079570 + 68 NuclAT_22 - -
- 2079503..2079570 + 68 NuclAT_22 - -
- 2079503..2079570 + 68 NuclAT_22 - -
- 2079503..2079570 + 68 NuclAT_22 - -
- 2079503..2079570 + 68 NuclAT_24 - -
- 2079503..2079570 + 68 NuclAT_24 - -
- 2079503..2079570 + 68 NuclAT_24 - -
- 2079503..2079570 + 68 NuclAT_24 - -
EJK95_RS10040 2079860..2080960 - 1101 WP_001295620.1 sodium-potassium/proton antiporter ChaA -
EJK95_RS10045 2081230..2081460 + 231 WP_001146442.1 putative cation transport regulator ChaB -
EJK95_RS10050 2081618..2082313 + 696 WP_001355927.1 glutathione-specific gamma-glutamylcyclotransferase -
EJK95_RS10055 2082357..2082710 - 354 WP_001169669.1 DsrE/F sulfur relay family protein YchN -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3983.80 Da        Isoelectric Point: 11.4779

>T286220 WP_000170954.1 NZ_LR130532:c2078384-2078277 [Escherichia coli]
MTLAQFAMIFWHDLAAPILAGIITAAIVGWWRNRK

Download         Length: 108 bp

Antitoxin


Download         Length: 67 bp

>AT286220 NZ_LR130532:2078432-2078498 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U9LPE9

Antitoxin

Download structure file

References