Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2282884..2283147 Replicon chromosome
Accession NZ_LR130518
Organism Staphylococcus aureus strain BPH2986 isolate BPH2986

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag EW031_RS12120 Protein ID WP_001802298.1
Coordinates 2283043..2283147 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2282884..2283048 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW031_RS12100 2279067..2279732 - 666 WP_001024094.1 SDR family oxidoreductase -
EW031_RS12105 2279884..2280204 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EW031_RS12110 2280206..2281186 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
EW031_RS12115 2281452..2282543 + 1092 WP_000495671.1 lytic regulatory protein -
- 2282884..2283048 + 165 - - Antitoxin
EW031_RS12120 2283043..2283147 - 105 WP_001802298.1 hypothetical protein Toxin
EW031_RS15525 2283308..2283791 - 484 Protein_2240 recombinase family protein -
EW031_RS12130 2283834..2284970 - 1137 WP_000115564.1 SAP domain-containing protein -
EW031_RS12135 2285259..2285351 + 93 WP_001790138.1 hypothetical protein -
EW031_RS12140 2286056..2286913 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
EW031_RS12145 2286981..2287763 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T286187 WP_001802298.1 NZ_LR130518:c2283147-2283043 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT286187 NZ_LR130518:2282884-2283048 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References