286177

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2712996..2713180 Replicon chromosome
Accession NZ_LR130515
Organism Staphylococcus aureus strain BPH2947 isolate BPH2947

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag EW033_RS14440 Protein ID WP_000482650.1
Coordinates 2713073..2713180 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2712996..2713056 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW033_RS14415 2708526..2708693 - 168 WP_001790576.1 hypothetical protein -
EW033_RS14425 2708924..2710657 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
EW033_RS14430 2710682..2712445 - 1764 WP_031873766.1 ABC transporter ATP-binding protein/permease -
- 2712996..2713056 + 61 - - Antitoxin
EW033_RS14440 2713073..2713180 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
EW033_RS14445 2713313..2713699 - 387 WP_000779358.1 flippase GtxA -
EW033_RS14450 2713967..2715109 + 1143 WP_001176863.1 glycerate kinase -
EW033_RS14455 2715169..2715828 + 660 WP_000831298.1 membrane protein -
EW033_RS14460 2716010..2717221 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
EW033_RS14465 2717344..2717817 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T286177 WP_000482650.1 NZ_LR130515:c2713180-2713073 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT286177 NZ_LR130515:2712996-2713056 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References