Detailed information of TA system TA286164

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1957923..1958105
• Replicon: chromosome
• Accession: NZ_LR130515
• Organism: Staphylococcus aureus strain BPH2947 isolate BPH2947

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: EW033_RS09980
• Protein ID: WP_001801861.1
• Coordinates: 1957923..1958018 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1958046..1958105 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EW033_RS09930	1953583..1954209	+	627	WP_000669046.1	hypothetical protein	-
EW033_RS09935	1954250..1954594	+	345	WP_000627551.1	DUF3969 family protein	-
EW033_RS09940	1954692..1955243	+	552	WP_000414205.1	hypothetical protein	-
EW033_RS09945	1955461..1956102	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
EW033_RS09950	1956216..1956401	-	186	WP_000809857.1	hypothetical protein	-
EW033_RS09955	1956403..1956579	-	177	WP_000375476.1	hypothetical protein	-
EW033_RS09960	1956590..1956973	-	384	WP_000070811.1	hypothetical protein	-
EW033_RS09970	1957577..1957720	-	144	WP_001549059.1	transposase	-
EW033_RS09980	1957923..1958018	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1958046..1958105	-	60	-	-	Antitoxin
EW033_RS09985	1958141..1958242	+	102	WP_001791893.1	hypothetical protein	-
EW033_RS09990	1958220..1958396	-	177	Protein_1879	transposase	-
EW033_RS09995	1958590..1958967	-	378	WP_001037045.1	DUF1433 domain-containing protein	-
EW033_RS10000	1959488..1960756	-	1269	Protein_1881	ATP-binding protein	-
EW033_RS10010	1960808..1961979	-	1172	Protein_1882	IS256-like element IS256 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1951023..1979352	28329

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T286164 WP_001801861.1 NZ_LR130515:1957923-1958018 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 60 bp

>AT286164 NZ_LR130515:c1958105-1958046 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin