Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2505304..2505488 Replicon chromosome
Accession NZ_LR130513
Organism Staphylococcus aureus strain BPH2900 isolate BPH2900

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag EW029_RS12930 Protein ID WP_000482647.1
Coordinates 2505381..2505488 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2505304..2505364 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW029_RS12920 2501100..2502833 - 1734 WP_000486501.1 ABC transporter ATP-binding protein/permease -
EW029_RS12925 2502858..2504621 - 1764 WP_001064811.1 ABC transporter ATP-binding protein/permease -
- 2505304..2505364 + 61 - - Antitoxin
EW029_RS12930 2505381..2505488 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
EW029_RS12935 2505622..2506008 - 387 WP_000779356.1 flippase GtxA -
EW029_RS12940 2506276..2507418 + 1143 WP_001176863.1 glycerate kinase -
EW029_RS12945 2507478..2508137 + 660 WP_000831298.1 membrane protein -
EW029_RS12950 2508316..2509527 + 1212 WP_061735511.1 multidrug effflux MFS transporter -
EW029_RS12955 2509650..2510123 - 474 WP_000456498.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T286160 WP_000482647.1 NZ_LR130513:c2505488-2505381 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT286160 NZ_LR130513:2505304-2505364 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References